Squamous cell carcinoma arising in transplanted skin

Squamous cell carcinoma arising in a skin graft is rare. Previous reports c oncern the use of skin in heterotopic locations namely the vagina and oral cavity. We report a case of squamous cell carcinoma, which arose in a skill graft used fur resurfacing a scalp defect. The defect followed the excisio n of a basal cell carcinoma 11 years previously The excision was incomplete and radiotherapy had been given. The possible pathological mechanisms for the development of a squamous cell carcinoma in transplanted skin are discu ssed.