Computer-assisted area measurement of skin lesions would be useful for the
assessment of disease severity. Difficulties can be encountered, however, w
hen lesions cannot simply be separated using the normal threshold tool of a
n image analyser. Owing to body curvature, peripheral sites are usually sha
dowed. To obtain a well-fitting curved line to account for body curvature-i
nduced glare and shadow, we devised a simple C-programme for averaging neig
hbouring pixels on the same horizontal line. An image was captured from a c
olour slide to the image analysis system. C++ was used for programming. Exe
cution of the averaging programme with the original image resulted in a bac
kground brightness image file. When this was subtracted from the original i
mage, the lesions were easily detected using the standard threshold tool an
d the percentage of area involved was calculated. This method is sufficient
ly accurate for the assessment of disease severity.