Low grade gastric MALT lymphoma: Radiographic findings

AIMS: Gastric MALT (mucosa-associated lymphoid tissue) lymphoma is now reco gnized as a distinct entity within extranodal non-Hodgkin's lymphoma. The p urpose of this study was to describe the radiographic findings in low grade gastric MALT lymphoma. MATERIALS AND METHODS: We retrospectively reviewed the radiographic finding s in 22 cases of low-grade gastric MALT lymphoma. The study group consisted of 15 men and seven women (median age 68 years, range 41-91 years). Lesion s were designated as infiltrative or polypoid by consensus of two radiologi sts. Polypoid lesions were categorized by number and size. Anatomical site within the stomach and presence of transpyloric or oesophagogastric extensi on was determined for each case, The presence of abdominal lymphadenopathy was categorized as regional or distant. The presence of Helicobacter pylori was determined from endoscopic and surgical biopsies, RESULTS: Computed tomography (CT) revealed abnormalities of the stomach in 19 cases of the 21 in which it was performed. There were 14 infiltrative le sions and five polypoid lesions. Of the 14 infiltrative lesions, the mean g astric wall thickness was 2.2 cm (range 0.8-6.0 cm), There were three singl e and two multiple polypoid lesions (mean size 2.2 cm, range 1.5-2.7 cm), T ranspyloric extension was observed in two cases and oesophagogastric extens ion in one. Abdominal lymphadenopathy was observed in 10 of 21 patients. He licobacter pylori was found in 19 of 22 cases (86%). CONCLUSION: Low grade B cell gastric MALT lymphomas present with an infiltr ative form on CT in about three-quarters of cases and a polypoid pattern in the remainder, Abdominal lymphadenopathy is seen in approximately one-half of cases. There is a high association with Helicobacter pylori, Brown, J. A. et nl. 2000. Clinical Radiology 55, 384-389. (C) 2000 The Royal College of Radiologists.