Human developmental biology of granulocyte colony-simulating factor

Authors
Calhoun, DA Christensen, RD
Citation
Da. Calhoun et Rd. Christensen, Human developmental biology of granulocyte colony-simulating factor, CLIN PERIN, 27(3), 2000, pp. 559
Citations number
122
Categorie Soggetti
Reproductive Medicine
Journal title
CLINICS IN PERINATOLOGY
ISSN journal
00955108 → ACNP
Volume
27
Issue
3
Year of publication
2000
Database
ISI
SICI code
0095-5108(200009)27:3<559:HDBOGC>2.0.ZU;2-B
Abstract
The availability of granulocyte colony-stimulating factor (G-CSF) has influ enced the management of neonates with neutropenia. Since the first use of G -CSF in a neonate with neutropenia, much has been learned about the cellula r sources and physiologic roles of G-CSF. This article reviews our present understanding of G-CSF and its cognate receptor in the fetus and neonate.