Genetic control of cell size

Authors
Stocker, H Hafen, E
Citation
H. Stocker et E. Hafen, Genetic control of cell size, CUR OP GEN, 10(5), 2000, pp. 529-535
Citations number
76
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN GENETICS & DEVELOPMENT
ISSN journal
0959437X → ACNP
Volume
10
Issue
5
Year of publication
2000
Pages
529 - 535
Database
ISI
SICI code
0959-437X(200010)10:5<529:GCOCS>2.0.ZU;2-J
Abstract
Over the past 25 years, the genetic control of cell size has mainly been ad dressed in yeast, a single-celled organism. Recent insights from Drosophila have shed light on the signalling pathways responsible for adjusting and m aintaining cell size in metazoans. Evidence is emerging for a signalling ca scade conserved in evolution that links external nutrient sources to cell s ize.