B. Karniol et Da. Chamovitz, The COP9 signalosome: from light signaling to general developmental regulation and back, CUR OPIN PL, 3(5), 2000, pp. 387-393
The COP9 signalosome has eight core subunits that are highly conserved betw
een plants and animals. Some of the subunits in Arabidopsis are found in fo
rms that are independent of the complex. The COP9 complex is essential for
animal development. The COP9 signalosome may have both an evolutionary and
a physical relationship with both the regulatory lid of the proteasome and
elF3.