Most chronic fatigue syndrome (CFS) studies are based on information about
patients from primary or tertiary care settings. These patients might not b
e typical of patients in the general population. This investigation involve
d examinations of individuals with CFS from a community-based study. A rand
om sample of 18,675 in Chicago was interviewed ed by telephone. Individuals
with chronic fatigue and at least four minor symptoms associated with CFS
were given medical and psychiatric examinations. A group of physicians then
diagnosed individuals with CFS, who were then subclassified based on three
sociodemographic categories-gender ethnicity, and work status. Sociodemogr
aphic sub-groups were analyzed in terms of symptom severity, functional dis
ability, coping, optimism perceived stress, and psychiatric comorbidity. Wo
men, minorities, and nonworking individuals with CFS reported greater level
s of functional disability symptom severity and poorer psychosocial functio
ning than men, Caucasians, and working individuals, suggesting sociodemogra
phic characteristics may be associated with poorer outcomes in urban, commu
nity-based samples of CFS individuals.