Hepatitis C virus (HCV) is transmitted primarily through direct percutaneou
s exposure to infected blood, Sporadic HCV cases exist and may represent mo
re than 10% of HCV transmission, We report the first case of documented tra
nsmission of HCV during a fight from a person who unknowingly had chronic H
CV infection to a person who subsequently contracted acute hepatitis C, Pat
ient-to-patient transmission was ascertained by sequence analysis of part o
f the NS5B genome and phylogenetic analysis. This case report suggests that
sporadic HCV infection may be a result of blood exposure. This example of
transmission could have a major impact in sports such as boxing or rugby, W
e suggest that in any fight, single use or nondisposable material should be
used to dry blood to avoid such contamination.