Syntheses of melatonin and its derivatives

Authors
Somei, M Fukui, Y Hasegawa, M Oshikiri, N Hayashi, T
Citation
M. Somei et al., Syntheses of melatonin and its derivatives, HETEROCYCLE, 53(8), 2000, pp. 1725
Citations number
32
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
53
Issue
8
Year of publication
2000
Database
ISI
SICI code
0385-5414(20000801)53:8<1725:SOMAID>2.0.ZU;2-E
Abstract
Two simple synthetic methods for melatonin are newly developed from tryptam ine through intermediates, which are promising lead compounds for drug deve loping research. Novel chemical reactivities of melatonin in its brominatio n, lithiation, and acylation are also reported.