A spontaneous teratoma was detected in the left testis of a 7-wk-old m
ale ICR (Crj:CD-1) mouse. The tumor was composed of a variety of well-
differentiated tissue elements from all 3 germ layers including neuron
al tissue and stratified epithelium as ectoderm-derived tissues, bone,
cartilage, striated muscle, and adipose tissue as mesodermal tissues,
and respiratory columnar epithelium as endoderm-originated tissue. No
tumor metastasis was detected. It may be of congenital origin as in s
train 129 mice. To the best of our knowledge, this is the first report
concerning spontaneous testicular teratoma in a strain ICR mouse.