Comparison of a ligase chain reaction-based assay and cell culture for detection of pharyngeal carriage of Chlamydia trachomatis

Authors
Winter, AJ Gilleran, G Eastick, K Ross, JDC
Citation
Aj. Winter et al., Comparison of a ligase chain reaction-based assay and cell culture for detection of pharyngeal carriage of Chlamydia trachomatis, J CLIN MICR, 38(9), 2000, pp. 3502-3504
Citations number
15
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
38
Issue
9
Year of publication
2000
Pages
3502 - 3504
Database
ISI
SICI code
0095-1137(200009)38:9<3502:COALCR>2.0.ZU;2-1
Abstract
In 264 genitourinary medicine clinic attenders reporting recent fellatio, t he prevalence of pharyngeal Chlamydia trachomatis determined by an expanded standard including cell culture and two in-house PCR tests was 1.5% in 194 women and zero in 70 men. The ligase chain reaction (Abbott LCx) had a spe cificity of 99.2% and a positive predictive value of 60%.