2-O-substituted-3,6-per-anhydro-alpha-cyclodextrin as potential biocompatible agents for the selective complexation of heavy metal ions with special attention to lead

Authors
Baudin, C Pean, C Pellizzari, B Gadelle, A Fauvelle, F Debouzy, JC Dalbiez, JP Perly, B
Citation
C. Baudin et al., 2-O-substituted-3,6-per-anhydro-alpha-cyclodextrin as potential biocompatible agents for the selective complexation of heavy metal ions with special attention to lead, J INCL P MA, 38(1-4), 2000, pp. 287-296
Citations number
17
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
ISSN journal
13883127 → ACNP
Volume
38
Issue
1-4
Year of publication
2000
Pages
287 - 296
Database
ISI
SICI code
1388-3127(200012)38:1-4<287:2APB>2.0.ZU;2-2
Abstract
We report on the synthesis, characterization and ionic complexation propert ies of hexakis (2-O-acetyl-3,6-anhydro) cyclomaltohexaose and hexakis (2-O- methyl-3,6-anhydro) cyclomaltohexaose using thin-layer chromatography and N uclear Magnetic Resonance spectroscopy. The selectivity towards cations dep ends on chemical modification of the hydroxyl groups and a very high specif icity can be obtained in the case of lead for methylated derivatives.