We are now able to analyze follow-lip delta up to 10 years after percutaneo
us mitral commissurotomy (PMC). In clinical terms, several large single-cen
ter series confirm the late efficacy of the procedure in a large population
comprising a variety of patient subsets. When the immediate results are un
satisfactory, prognosis is poor and surgery should be carried out when the
clinical conditions allow it. Conversely, if PMC is initially successful, t
he clinical results are excellent and late deterioration is mainly related
to restenosis. Preliminary series have shown that repeat balloon commissuro
tomy may be performed successfully in such patients. The prediction of late
results after balloon commissurotomy is multifactorial and based on clinic
al parameters, valve anatomy, and the immediate results of the procedure. R
andomized studies have shown that the long-term results of balloon commissu
rotomy are as good as those of surgery in patients with favorable character
istics. in the others, there has been no comparative study and patient sele
ction should take into account the multifactorial nature of the prediction
of late results. Overall, these good long-term results have led to an incre
ased use of balloon commissurotomy in the treatment of patients patients wi
th mitral stenosis.