AGED GARLIC EXTRACT AND ITS CONSTITUENTS INHIBIT CU2-INDUCED OXIDATIVE MODIFICATION OF LOW-DENSITY-LIPOPROTEIN()

Authors
IDE N NELSON AB LAU BHS
Citation
N. Ide et al., AGED GARLIC EXTRACT AND ITS CONSTITUENTS INHIBIT CU2-INDUCED OXIDATIVE MODIFICATION OF LOW-DENSITY-LIPOPROTEIN(), Planta medica, 63(3), 1997, pp. 263-264
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences","Chemistry Medicinal
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
63
Issue
3
Year of publication
1997
Pages
263 - 264
Database
ISI
SICI code
0032-0943(1997)63:3<263:AGEAIC>2.0.ZU;2-U
Abstract
Oxygen radical injury and lipid peroxidation have been suggested as ma jor causes of atherosclerosis, cancer, liver disease, and the aging pr ocess. More specifically, oxidative modification of low density lipopr otein (LDL) has been recognized as an important process of atheroscler osis. In this study, we determined the effects of aged garlic extract (AGE), four of its constituents, and a metabolite on Cu2+-induced oxid ative modification of LDL using an in vitro system. All these compound s were shown to inhibit oxidative modification of LDL.