Intramedullary ependymomas: clinical presentation, surgical treatment strategies and prognosis

Citation
Th. Schwartz et Pc. Mccormick, Intramedullary ependymomas: clinical presentation, surgical treatment strategies and prognosis, J NEURO-ONC, 47(3), 2000, pp. 211-218
Citations number
45
Categorie Soggetti
Oncology
Journal title
JOURNAL OF NEURO-ONCOLOGY
ISSN journal
0167594X → ACNP
Volume
47
Issue
3
Year of publication
2000
Pages
211 - 218
Database
ISI
SICI code
0167-594X(200005)47:3<211:IECPST>2.0.ZU;2-T
Abstract
Intramedullary ependymomas are rare tumors but comprise the majority of int ramedullary glial neoplasms in the adult. These tumors are benign, slow-gro wing lesions which are optimally treated with gross-total surgical resectio n without adjuvant therapy. This objective can be attained safely in a majo rity, of patients. Post-operative functional outcome is related to pre-oper ative functional status. Hence, early diagnosis, prior to symptomatic progr ession, is critical to the successful treatment of these tumors. Adjuvant t herapy is indicated for the rare malignant or disseminated tumor or followi ng sub-total resection.