Gr. Mokhlis et al., A clinical evaluation of carbamide peroxide and hydrogen peroxide whitening agents during daytime use, J AM DENT A, 131(9), 2000, pp. 1269-1277
Background, Vital tooth bleaching for esthetic reasons has gained in popula
rity during the last few years. However, few studies have investigated the
efficacy of daytime bleaching products. The purpose of this double-blind in
vivo study was to evaluate the efficacy of 20 percent carbamide peroxide,
or CP, and 7.5 percent hydrogen peroxide, or KP, during daytime use. The de
gree of color change, any color relapse, and tooth or gingival sensitivity
were evaluated.
Methods, Twenty-four patients participated in this Study. The bleaching gel
s were randomly applied to the right and left maxillary anterior teeth. Pat
ients were shown how to place the two bleaching agents in a custom tray for
one hour, twice a day for two weeks. Patients returned in one, two, three,
six and 12 weeks for color evaluation with the colorimeter and shade guide
s as well as to have color slide photographs taken. The authors evaluated s
ensitivity by asking the patients to record daily for 21 days any tooth or
gingival sensitivity they experienced.
Results. Use of the 20 percent CP resulted in significantly more lightness
than the 7.5 percent HP during the first 14 days of the study, but at the e
nd of the study, there was no significant difference between products with
regard to tooth lightness. In addition, the authors found no statistically
significant difference between products with regard to gingival or tooth se
nsitivity.
Conclusions. Both CP and HP are effective at-home bleaching agents when day
time bleaching is preferred.
Clinical Implications- Dentists who choose to use daytime bleaching can sel
ect either CP or HP.