THE QUEST FOR MIGRAINE GENES

Authors
TERWINDT GM HAAN J OPHOFF RA FRANTS RR FERRARI MD
Citation
Gm. Terwindt et al., THE QUEST FOR MIGRAINE GENES, Current opinion in neurology, 10(3), 1997, pp. 221-225
Citations number
56
Categorie Soggetti
Neurosciences,"Clinical Neurology
Journal title
Current opinion in neurology → ACNP
ISSN journal
13507540
Volume
10
Issue
3
Year of publication
1997
Pages
221 - 225
Database
ISI
SICI code
1350-7540(1997)10:3<221:TQFMG>2.0.ZU;2-F
Abstract
Research into the genetics of migraine remains difficult because of th e involvement of polygenetic and environmental factors. The discovery of the gene for familial hemiplegic migraine on chromosome 19p13 is an important step forward. This brain specific P/Q-type calcium channel alpha 1-subunit gene opens new avenues for studying the genetics of mi graine, the pathophysiology of the onset of migraine attacks and the d evelopment of novel specific prophylactic drugs.