Spontaneous clearance of hepatitis C virus infection post-liver transplantation is associated with rapidly changing quasispecies: A single case report

Hepatitis C virus (HCV) clearance post-liver transplantation is uncommon, T his is a case report of a patient who, after liver transplantation, develop ed cholestatic hepatitis characterized by severe graft dysfunction, in conj unction with high viral load. This was, however, followed by viral clearanc e and normalization of allograft function. The clinical features of this ca se and the quasispecies patterns during the illness and the clearance perio ds are described. In addition, management implications in terms of immunosu ppressive therapy are discussed.