Artificial blood pumps play an increasingly important role in the treatment
of end-stage cardiac failure. The fluid dynamics of blood flow through suc
h devices crucially affects their clinical effectiveness. Specifically, if
the flow of blood stagnates or slowly re-circulates thrombus formation can
occur and the avoidance of such flow features is a primary consideration in
the design of pumps. The present study concerns the development of a fluor
escent particle visualisation technique and its application to investigate
the flow environments in four prototype blood pump designs. The procedure i
nvolves recording video images of eight illuminated cross sections through
the pumping chambers as the pumps operate in a mock circulatory loop using
a test fluid seeded with fluorescent particles. The technique enabled a sem
i-quantitative characterisation of the entire flow field, throughout the pu
mping cycle, to be performed for each pump design. Flow features were then
related to design properties of the individual pumps and recommendations ma
de for design optimisation. (C) 2000 IPEM. Published by Elsevier Science Lt
d. All rights reserved.