A three-dimensional capsular bag model for investigating the biomechanicalproperties of newly designed intraocular lenses

Background. This study quantified the geometric deformation of the capsular bag following implantation of various intraocular lenses (IOL) using a thr ee-dimensional capsular bag model made of silicone caoutchouc. Methods. After implantation of 13 different IOLs (polymethylmethacrylate, s ilicone acrygel) into the artificial bag, the induced capsular bag deformat ion was measured and analyzed. The posterior space between IOL and capsule was examined by ultrasonographic biomicroscopy. Results. Polymethylmethacrylate IOLs with C-haptic design induced a greater deformation of the capsular bag than silicone lenses; however, both types showed a larger gap posterior to the IOL than acrygel lenses. Acrygel IOLs with different haptic design revealed only minimal deformation with close c ontact posteriorly. Conclusions. The presented three-dimensional model simulates the biomechani cal and geometrical parameters of the vital capsular bag. Further investiga tions may determine a correlation of close posterior IOL contact and lens e pithelial cell progression.