Efficient one-step conversion of primary aliphatic amines into primary alcohols: Application to a model study for the total synthesis of (+/-)-scopadulin

Authors
Rahman, SMA Ohno, H Maezaki, N Iwata, C Tanaka, T
Citation
Sma. Rahman et al., Efficient one-step conversion of primary aliphatic amines into primary alcohols: Application to a model study for the total synthesis of (+/-)-scopadulin, ORG LETT, 2(18), 2000, pp. 2893-2895
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
18
Year of publication
2000
Pages
2893 - 2895
Database
ISI
SICI code
1523-7060(20000907)2:18<2893:EOCOPA>2.0.ZU;2-D
Abstract
Treatment of primary aliphatic amines with KOH in diethylene glycol at 210 degrees C gives primary alcohols directly in good yields. A synthetic appli cation to a model study of (+/-)-scopadulin is also described. [Graphics]