To assess the diagnostic value of an extensive cardiac screening and o
f carotid artery duplex scanning in patients suspected of suffering fr
om retinal embolism, we examined 41 consecutive patients (mean age 59.
6 years, range 36-74) who presented either with amaurosis fugax or wit
h a retinal artery occlusion. In spite of extensive investigations, we
found no cause in 27 patients (66%). In 11 patients (27%), symptoms w
ere likely to be due to a stenosis or an occlusion of the ipsilateral
carotid artery. In only 1 patient (2%), the heart was likely to be a s
ource of embolism. We conclude that in patients in this age group suff
ering from either amaurosis fugax or a retinal artery occlusion, a car
otid artery duplex scanning should be performed first as this investig
ation is more likely to provide useful information than an extensive c
ardiac screening (ECG, Holter 24-hour monitoring and precordial echoca
rdiography).