2-amino-6-(1,2,4-triazol-4-yl)-purine: a useful intermediate in the synthesis of 9-alkylguanines

Authors
Alarcon, K Martelli, A Demeunynck, M Lhomme, J
Citation
K. Alarcon et al., 2-amino-6-(1,2,4-triazol-4-yl)-purine: a useful intermediate in the synthesis of 9-alkylguanines, TETRAHEDR L, 41(37), 2000, pp. 7211-7215
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
37
Year of publication
2000
Pages
7211 - 7215
Database
ISI
SICI code
0040-4039(20000909)41:37<7211:2AUIIT>2.0.ZU;2-L
Abstract
2-Amino-6-(1,2,4-triazol-4-yl)purine, prepared from 2,6-diaminopurine, was regioselectively alkylated at position 9. Subsequent alkaline hydrolysis af forded 9-alkylguanines in high yield. (C) 2000 Elsevier Science Ltd. All ri ghts reserved.