The direct synthesis of novel enantiomerically pure alpha-amino acids in protected form via Suzuki cross-coupling

Authors
Collier, PN Campbell, AD Patel, I Taylor, RJK
Citation
Pn. Collier et al., The direct synthesis of novel enantiomerically pure alpha-amino acids in protected form via Suzuki cross-coupling, TETRAHEDR L, 41(36), 2000, pp. 7115-7119
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
36
Year of publication
2000
Pages
7115 - 7119
Database
ISI
SICI code
0040-4039(20000902)41:36<7115:TDSONE>2.0.ZU;2-U
Abstract
Protected allylglycine has been hydroborated and the intermediate organobor ane employed in Suzuki coupling reactions with a number of olefinic, aromat ic and heteroaromatic bromides and iodides to produce a range of novel a-am ino acids in good, unoptimised yields. (C) 2000 Elsevier Science Ltd. All r ights reserved.