A CLASSICAL BOWMAN-BIRK SOYBEAN INHIBITOR ACTS AS AN EFFECTIVE INHIBITOR OF HUMAN GRANULOCYTE ALPHA-CHYMOTRYPSIN AND CATHEPSIN-G

Authors
GLADYSHEVA IP LARIONOVA NI GLADYSHEV DP TIKHONOVA TV KAZANSKAYA NF
Citation
Ip. Gladysheva et al., A CLASSICAL BOWMAN-BIRK SOYBEAN INHIBITOR ACTS AS AN EFFECTIVE INHIBITOR OF HUMAN GRANULOCYTE ALPHA-CHYMOTRYPSIN AND CATHEPSIN-G, Biochemistry, 59(4), 1994, pp. 371-374
Citations number
40
Categorie Soggetti
Biology
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
59
Issue
4
Year of publication
1994
Pages
371 - 374
Database
ISI
SICI code
0006-2979(1994)59:4<371:ACBSIA>2.0.ZU;2-7
Abstract
The interaction of a classical Bowman-Birk soybean inhibitor (BBI 2-IV ) with human granulocyte alpha-chymotrypsin and cathepsin G was studie d kinetically. The rate constants determined for the inhibitor-protein ase systems were 2.0.10(5) M(-1).sec(-1) and 6.410(6) M (-1).sec(-1) f or alpha-chymotrypsin and cathepsin G, respectively.