Organometal-catalyzed asymmetric synthesis stereocontrolled by organosulfur functionality

Our recent studies on asymmetric synthesis with the assistance of organomet al catalysts stereocontrolled by organosulfur functionality involved in rea ction substrates or ligands are reviewed. The studies focused on asymmetric synthesis via chiral pi-allylmetal complexes derived from (S)-proline ally l ester, olefinic cyclopropanes, chiral 2-alkynyl sulfinates, and chiral ne w ligands, and also focused on asymmetric cycloaddition reactions with chir al sulfoxides and sulfinates, such as intramolecular ene, metallo-type ene, and hetero Diels-Alder reactions. Participation of organosulfur functional ity in organometal-catalyzed asymmetric reactions was unveiled on the basis of the stereochemical outcomes obtained.