We recently treated two cases of chronic pancreatitis with obstructive jaun
dice due to compression of the common bile duct by pancreatic pseudocyst. T
he two cases were males admitted with the complaint of icteric skin color.
The first, a 46-year-old male, admitted with the complaint of icteric skin
color. He was treated by operative cystojejunostomy after percutaneous drai
nage of the pseudocyst and percutaneous transhepatic biliary drainage. The
other case was a 58 year-old male who admitted with the complaint of icteri
c skin color. He had an infected pseudocyst in the pancreas and was endosco
pically treated. Both of them were discharged with favorable clinical cours
e and normal laboratory findings after the treatment. The former patient re
mained well 11 months after treatment, but the latter patient died from nec
rotizing pancreatitis and septic shock 6 months after treatment. Most cases
of obstructive jaundice associated with pseudocysts appear to be due to fi
brotic stricture of the intrapancreatic portion of the common bile duct rat
her than due to compression of the bile duct by the pseudocyst. In a patien
t with secondary pancreatic infection or obstructive jaundice following pan
creatic disease, differentiating between these two conditions is an importa
nt aspect of accurate diagnosis and therapy. Herein we report two unusual c
ases of chronic pancreatitis with pseudocyst complicated by obstructive jau
ndice.