Advances in minimally invasive surgery have made possible a laparoscopic ap
proach for several retroperitoneal pathologies. Many studies have shown tha
t laparoscopic adrenalectomy is the new gold standard of care particularly
for benign lesions. The most serious endoscopic technical problem is the bl
eeding control. We suggest the use of fibrin sealant during lateral transpe
ritoneal laparoscopic adrenalectomy could improve hemostasis and postoperat
ive morbidity.