Bilateral uveal effusion associated with scleral thickening due to amyloidosis

A 45-year-old man with primary systemic amyloidosis was found to have bilat eral uveal effusions secondary to thickened sclera according to magnetic re sonance imaging of the orbits. The patient was treated with bilateral scler ectomies and vortex vein decompression, and had an excellent outcome. Light microscopy of excised sclera revealed severe infiltration of the tissue by amyloid. To our knowledge, this is the first report of amyloid infiltratio n of the sclera leading to uveal effusion.