Structures of photointermediates and their implications for the proton pump mechanism

Authors
Kataoka, M Kamikubo, H
Citation
M. Kataoka et H. Kamikubo, Structures of photointermediates and their implications for the proton pump mechanism, BBA-BIOENER, 1460(1), 2000, pp. 166-176
Citations number
39
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
ISSN journal
00052728 → ACNP
Volume
1460
Issue
1
Year of publication
2000
Pages
166 - 176
Database
ISI
SICI code
0005-2728(20000830)1460:1<166:SOPATI>2.0.ZU;2-1
Abstract
It is widely accepted that bacteriorhodopsin undergoes global conformationa l changes during its photocycle. In this review, the structural properties of the M and N intermediates are described in detail. Based on the clarifie d global conformational change, we propose a model for the molecular mechan ism of the proton pump. The global structural change is suggested to be a k ey component in establishing vectorial proton transport. (C) 2000 Elsevier Science B.V. All rights reserved.