The brain-specific G-protein coupled receptor GPR85 with identical proteinsequence in man and mouse maps to human chromosome 7q31

Authors
Hellebrand, S Schaller, HC Wittenberger, T
Citation
S. Hellebrand et al., The brain-specific G-protein coupled receptor GPR85 with identical proteinsequence in man and mouse maps to human chromosome 7q31, BBA-GENE ST, 1493(1-2), 2000, pp. 269-272
Citations number
21
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1493
Issue
1-2
Year of publication
2000
Pages
269 - 272
Database
ISI
SICI code
0167-4781(20000907)1493:1-2<269:TBGCRG>2.0.ZU;2-J
Abstract
A new G-protein coupled receptor, GPR85, was identified in man and mouse, w hich is completely conserved at the amino acid level. Transcripts of gpr85 were found in several human brain regions and, at lower levels, in spleen a nd placenta, whereas in mouse, gpr85 is confined to the brain. The hgpr85 g ene was localized to human chromosome 7q31 by the polymerase chain reaction utilizing a radiation hybrid panel. (C) 2000 Elsevier Science B.V. All rig hts reserved.