Computation of writhe in modeling of supercoiled DNA

Authors
Klenin, K Langowski, J
Citation
K. Klenin et J. Langowski, Computation of writhe in modeling of supercoiled DNA, BIOPOLYMERS, 54(5), 2000, pp. 307-317
Citations number
21
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOPOLYMERS
ISSN journal
00063525 → ACNP
Volume
54
Issue
5
Year of publication
2000
Pages
307 - 317
Database
ISI
SICI code
0006-3525(20001015)54:5<307:COWIMO>2.0.ZU;2-1
Abstract
We describe four previously unpublished methods allowing the computation of the writhe for a supercoiled DNA molecule modeled by a polymer chain consi sting of straight segments. These methods are compared with each other in t erms of computational efficiency and the scope of their applicability is di scussed. (C) 2000 John Wiley & Sons, Inc.