Best design of heterogenized beta-aminoalcohols for improvement of enantioselective addition of diethylzinc to benzaldehyde

Authors
Abramson, S Lasperas, M Galarneau, A Desplantier-Giscard, D Brunel, D
Citation
S. Abramson et al., Best design of heterogenized beta-aminoalcohols for improvement of enantioselective addition of diethylzinc to benzaldehyde, CHEM COMMUN, (18), 2000, pp. 1773-1774
Citations number
15
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
18
Year of publication
2000
Pages
1773 - 1774
Database
ISI
SICI code
1359-7345(2000):18<1773:BDOHBF>2.0.ZU;2-Y
Abstract
Covalent immobilization of (1R,2S)-(-)-ephedrine, used as a model molecule of beta-aminoalcohols, on the surface of MCM-41-type mesoporous aluminosili cates, performed by a new sol-gel method, leads to chiral auxiliaries which show greatly enhanced rates and ee's compared to those reported up to now in the enantioselective addition of diethylzinc to benzaldehyde.