This review constitutes the first of four reviews that systematically addre
ss contemporary knowledge about the mechanical behavior of the cervical ver
tebrae and the soft-tissues of the cervical spine, under normal conditions
and under conditions that result in minor or major injuries. This first rev
iew considers the normal kinematics of the cervical spine, which predicates
the appreciation of the biomechanics of cervical spine injury. It summariz
es the cardinal anatomical features of the cervical spine that determine ho
w the cervical vertebrae and their joints behave. The results are collated
of multiple studies that have measured the range of motion of individual jo
ints of the cervical spine. However, modern studies are highlighted that re
veal that, even under normal conditions, range of motion is not consistent
either in time or according to the direction of motion. As well, detailed s
tudies are summarized that reveal the order of movement of individual verte
brae as the cervical spine flexes or extends. The review concludes with an
account of the location of instantaneous centres of rotation and their biol
ogical basis. (C) 2000 Elsevier Science Ltd. All rights reserved.