In the period between 1990 and 1996, 279 endosteal dental Bone-Lock implant
s were placed in 79 patients. Of them 63 have been treated with ablative tu
mor and reconstructive surgery in the oral cavity, the rest presented with
maxillo-mandibular defects of different origin. The circumstances of implan
t loss were noted down for descriptive analysis concerning age, sex, topogr
aphy, implant dimensions, loading, time in place and type of superstructure
. Failure analysis was done concerning the implants and the patients. Five
causes for implant loss could be detected: lacking primary osseointegration
, acute inflammation, bone loss, biomechanical overloading and tumor recurr
ence. No predictive factors for implant loss and no age influence on implan
t loss could be detected, no specific local implant site and no specific su
perstructure had an identifiable higher risk. Survival rate of all placed i
mplants in oral tumor and defect patients was 83.5% after 6 years observati
on. Male tumor patients were found to have a higher risk to lose implants t
han females. Free iliac bone grafts impaired osseointegration of implants.
The mandible offered a better prognosis for the implants than the maxilla.
Shorter and thinner implants had a higher risk of being lost. A quarter of
all patients (26.3%) had to face implant loss. Clustering of implant loss i
n several patients was caused by free iliac bone grafting and by prosthetic
faults. Chemotherapy had no negative influence on implant survival. Most i
mplants were lost early (76%) before fabrication of the prosthesis. After r
estoration there was a nearly 100% probability of function. It is concluded
that implant treatment can be equally effective for tumor and defect patie
nts as it is known for healthy subjects.