Vegetation records spanning the past 21 kyr in western North America d
isplay spatial patterns of change that reflect the influence of variat
ions in the large-scale controls of climate(1). Among these controls a
re millennial-scale variations in the seasonal cycle of insolation and
the size of the ice sheet, which affect regional climates directly th
rough changes in temperature and net radiation, and indirectly by shif
ting atmospheric circulation. Longer vegetation records provide an opp
ortunity to examine the regional response to different combinations of
these large-scale controls, and whether non-climatic controls are imp
ortant. But most of the longer North American records(2,3) are of insu
fficient quality to allow a robust test, and the Long European records
(4-9) are in regions where the vegetation response to climate is often
difficult to separate from the response to ecological and anthropogen
ic controls. Here we present a 125-kyr record of vegetation and climat
e change for the forest/steppe border of the eastern Cascade Range, no
rthwest America. Pollen data disclose alternations of forest and stepp
e that are consistent with variations in summer insolation and global
ice-volume, and vegetational transitions correlate well with the marin
e isotope-stage boundaries. The close relationship between vegetation
and climate beyond the Last Glacial Maximum provides evidence that cli
mate variations are the primary cause of regional vegetation change on
millennial timescales, and that non-climatic controls are secondary.