Cb. Vitale et al., SYSTEMIC LUPUS-ERYTHEMATOSUS IN A CAT - FULFILLMENT OF THE AMERICAN-RHEUMATISM-ASSOCIATION CRITERIA WITH SUPPORTIVE SKILL HISTOPATHOLOGY, Veterinary dermatology, 8(2), 1997, pp. 133-138
Systemic lupus erythematosus (SLE) was diagnosed in a 9-year-old castr
ated male Persian cat. The cat described is the first to fulfil four o
f 11 American Rheumatism Association criteria for the diagnosis of SLE
in humans (symmetrical facial dermatitis, thrombocytopenia, positive
antinuclear antibodies, oral ulceration) with supportive skin histopat
hology. Haematological abnormalities included a mild anaemia and sever
e thrombocytopenia. Skin disease consisted of symmetrical multifocal a
lopecia with crusting, predominantly on the face. Histopathology of th
e skin revealed interface dermatitis and interface folliculitis with f
ollicular atrophy. Complete remission was obtained with corticosteroid
therapy.