The fatty esters of 5-caffeoyl quinic acid were synthesized by direct ester
ification biocatalysed by an immobilised lipase obtained from Candida antar
ctica. Esterification yields (from 40 to 75%) depended on the carbon chain
length of the fatty alcohols and whether or not solvent (e-methyl 2-butanol
) was present in the reaction medium.