Histidine decarboxylase activity has been investigated in 23 strains of lac
tic acid bacteria, belonging to Oenococcus oeni, Lactobacillus brevis and L
actobacillus spp., isolated during the cidermaking process at different sta
ges of fermentation. After 14 days at 25 degrees C on a semisynthetic mediu
m supplemented with L-histidine, 13 strains were histamine producers and si
x of these strains were selected to study the kinetics of growth and histam
ine production at different temperatures. The results showed that histamine
accumulation was maximal at 25 degrees C after 10-15 days of growth. Compa
rison of growth and histamine level curves demonstrated a delay time of eig
ht days between maximal growth and the highest histamine content of the cul
tures.