Screening for iron overload and HFE mutations in a university hospital

Authors
Remacha, AF Carrasco, M Sarda, MP Barcelo, MJ Blesa, I Baiget, M
Citation
Af. Remacha et al., Screening for iron overload and HFE mutations in a university hospital, HAEMATOLOG, 85(8), 2000, pp. 873-874
Citations number
10
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
8
Year of publication
2000
Pages
873 - 874
Database
ISI
SICI code
0390-6078(200008)85:8<873:SFIOAH>2.0.ZU;2-E
Abstract
Hereditary hemochromatosis (HH) screening is based on transferrin saturatio n and serum ferritin concentration. These criteria are used in hospitals al though many patients without HH show the same iron abnormalities. Our study detected the HFE mutations in only a few patients (5 out of 55) who had a positive screening test. In hospitals additional criteria (hepatitis, alcoh olism, etc.) should be considered.