Platelet cryopreservation using second-messenger effectors and low-dose (2%) dimethyl sulfoxide. In vitro evaluation of post-thawing platelet activity with the platelet function analyzer

Authors
Borzini, P Lazzaro, A Mazzucco, L Schiavo, R Connor, J Siena, S
Citation
P. Borzini et al., Platelet cryopreservation using second-messenger effectors and low-dose (2%) dimethyl sulfoxide. In vitro evaluation of post-thawing platelet activity with the platelet function analyzer, HAEMATOLOG, 85(8), 2000, pp. 885-887
Citations number
9
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
8
Year of publication
2000
Pages
885 - 887
Database
ISI
SICI code
0390-6078(200008)85:8<885:PCUSEA>2.0.ZU;2-E
Abstract
Second-messenger effectors (ThromboSol(R)), together with low-dose dimethyl sulfoxide (DMSO) (2%), are described as a new cryopreservation solution. T he solution allows high yield recovery of cryopreserved platelets with a re sidual platelet function equal or superior to that of 6% DMSO-cryopreserved platelets. The hemostatic function of cryopreserved platelets was measured by PFA-100(TM).