Pregnancy outcome in renal transplant recipients

Objective: To correlate pregnancy outcome with complications in pregnancy a nd transplantation-to-pregnancy interval in renal transplant recipients in Croatia. Method: Data on 23 pregnancies after prepregnancy stabilization of blood pressure and normalization of graft function were retrospectively an alyzed. Result: The mean interval between transplantation and conception wa s 3.1 years. Primary renal disease was chronic glomerulonephritis in 7, chr onic pyelonephritis in 7 and agenesis of right kidney and stenosis of left renal artery in 1 patient. There were 10 term and 5 preterm deliveries, 6 i nduced and 2 spontaneous abortions. The mean gestational age was 38.1 weeks and the mean newborn birthweight was 3015 g. The prematurity rate was 21.7 %. Patients with arterial hypertension in pregnancy, elevated serum creatin ine level and bacteriuria, as well as those with conception occurring less than 2 years after transplantation, had a higher rate of therapeutic and sp ontaneous abortions, preterm deliveries and low birth weight infants. Concl usion: The interval between transplantation and conception, as well as allo graft function during pregnancy, seem to be of great importance for success ful obstetric outcome in renal transplant patients. (C) 2000 International Federation of Gynecology and Obstetrics.