DETERMINATION OF CHIMAPHILIN IN CHIMAPHIL A-UMBELLATA PRIMARY TINCTURE BY DIFFERENTIAL-PULSE POLAROGRAPHY

Authors
MICHELITSCH A ZELLNIG K BAUMEISTER A SCHUBERTZSILAVECZ M LIKUSSAR W
Citation
A. Michelitsch et al., DETERMINATION OF CHIMAPHILIN IN CHIMAPHIL A-UMBELLATA PRIMARY TINCTURE BY DIFFERENTIAL-PULSE POLAROGRAPHY, Die Pharmazie, 52(6), 1997, pp. 451-453
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
52
Issue
6
Year of publication
1997
Pages
451 - 453
Database
ISI
SICI code
0031-7144(1997)52:6<451:DOCICA>2.0.ZU;2-N
Abstract
In this paper a method for the determination of chimaphilin in plant e xtracts by differential pulse polarograpy (DPP) is presented. Chimaphi lin is reduced at the dropping mercury electrode at pH 7.2 and a poten tial of -0.270 V vs Ag/AgCl. Strict linearity between the chimaphilin concentration and the peak height was observed in the 2.7 . 10(-7) - 2 .7 . 10(-5) M concentration range. The detection limit is 40 ng/ml. Th e analysis of three equivalent extracts led to concentrations of 175.3 , 199.4 and 267.9 mu g chimaphilin per ml of primary tincture.