Advances in column technology and instrumentation in capillary electrochromatography

Capillary electrochromatography (CEC) is an emerging technique gaining incr eased interest. Improvement of instrumentation and column technology will b e of prime importance for the further development of this technique and its use in validated methods. In this paper, developments in column technology and instrumentation for CEC are reviewed with emphasis on developments wit hin the last 3 years. Attention is directed to the employment of stationary phases specifically designed for CEC, the use of soft and rigid gels in pl ace of packings, fritless packed capillaries, column dimensions, the optimi zation of injection and detection parameters, and gradient elution CEC. (C) 2000 Elsevier Science B.V. All rights reserved.