Chronic parvovirus B-19 meningoencephalitis with additional detection of Epstein-Barr virus DNA in the cerebrospinal fluid of an immunocompetent patient

Authors
Druschky, K Walloch, T Heckmann, J Schmidt, B Stefan, P Neundorfer, B
Citation
K. Druschky et al., Chronic parvovirus B-19 meningoencephalitis with additional detection of Epstein-Barr virus DNA in the cerebrospinal fluid of an immunocompetent patient, J NEUROVIRO, 6(5), 2000, pp. 418-422
Citations number
17
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF NEUROVIROLOGY
ISSN journal
13550284 → ACNP
Volume
6
Issue
5
Year of publication
2000
Pages
418 - 422
Database
ISI
SICI code
1355-0284(200010)6:5<418:CPBMWA>2.0.ZU;2-D
Abstract
Parvovirus B19 DNA was detected by polymerase chain reaction in the brain b iopsy specimen from a 67-year-old immunocompetent woman with severe chronic lymphocytic meningoencephalitis. In addition to parvovirus B19, Epstein-Ba rr virus DNA was identified in the CSF. Genomic material from Epstein-Barr virus was absent in the brain tissue. Clinical symptoms and CSF pleocytosis improved under long-term corticosteroid-treatment. The aetiopathogenetic r ole of parvovirus B19 and the possible meaning of the additionally detected Epstein-Barr virus DNA are discussed.