Acute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide

Authors
Felmet, K Robins, B Tilford, D Hayflick, SJ
Citation
K. Felmet et al., Acute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide, J PEDIAT, 137(3), 2000, pp. 427-428
Citations number
10
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
JOURNAL OF PEDIATRICS
ISSN journal
00223476 → ACNP
Volume
137
Issue
3
Year of publication
2000
Pages
427 - 428
Database
ISI
SICI code
0022-3476(200009)137:3<427:ANDIAI>2.0.ZU;2-G
Abstract
After exposure to nitrous oxide, an infant with unrecognized cobalamin defi ciency developed neurologic deterioration and pancytopenia. Hematologic rec overy and partial resolution of his neurologic changes followed repletion o f the vitamin. Nitrous oxide depletes bioavailable cobalamin and may be a d angerous anesthetic in patients with cobalamin deficiency.