Purpose: The purpose of this study was to determine, in a randomized clinic
al trial of 439 individuals with knee osteoarthritis, the incremental cost-
effectiveness of aerobic versus weight resistance training, compared with a
n education control intervention. Methods: Cost estimates of the interventi
on were based upon the cost of purchasing from the community similar servic
es to provide exercise or health education. Effect at 18 months was measure
d using several variables, including: self-reported disability score. 6-min
walking distance, stair climb, Lifting and carrying task, car task, and me
asures of pain frequency and pain intensity on ambulation and transfer. Res
ults: The total cost of the educational intervention was $343.98 per partic
ipant. The aerobic exercise intervention cost $323.55 per participant, and
the resistance training intervention cost $325.20 per participant. On all b
ut two of the outcome variables, the incremental savings per incremental ef
fect for the resistance exercise group was greater than for the aerobic exe
rcise group. Conclusion: The data obtained from this study suggest that, co
mpared with an education control, resistance training for seniors with knee
osteoarthritis is more economically efficient than aerobic exercise in imp
roving physical function. However, the magnitude of the difference in effic
iency between the two approaches is small.