Endospores of Bacillus spp., especially Bacillus subtilis, have served as e
xperimental models for exploring the molecular mechanisms underlying the in
credible longevity of spores and their resistance to environmental insults.
In this review we summarize the molecular laboratory model of spore resist
ance mechanisms and attempt to use the model as a basis for exploration of
the resistance of spores to environmental extremes both on Earth and during
postulated interplanetary transfer through space as a result of natural im
pact processes.