A table-top prototype has been constructed that uses the enzyme malate dehy
drogenase to recognize input signal patterns. The device is controlled by t
he enzyme in response to injection of Mg2+ used as a signaling substance. O
utput is monitored spectroscopically. If Mg2+ is injected along either of t
wo signal lines (i.e., if the input signal pattern is 10 or 01) the device
emits an output of 1. Injection along neither or both lines results in an o
utput of 0. The enzyme in effect is used as a transform that converts the l
inearly inseparable exclusive-or problem into a linearly separable problem.