A NOVEL REARRANGEMENT OF STEROIDAL ALPHA-HYDROXY OXIMES

Authors
MILJKOVIC D PENOVGASI K DJURENDIC E SAKAC M MEDICMIJACEVIC L PEJANOVIC V STANKOVIC S LAZAR D
Citation
D. Miljkovic et al., A NOVEL REARRANGEMENT OF STEROIDAL ALPHA-HYDROXY OXIMES, Tetrahedron letters, 38(26), 1997, pp. 4683-4684
Citations number
1
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
26
Year of publication
1997
Pages
4683 - 4684
Database
ISI
SICI code
0040-4039(1997)38:26<4683:ANROSA>2.0.ZU;2-N
Abstract
By the action of acidic titanium trichloride upon 16-oximino-17 alpha- benzyl-17 beta-hydroxy derivatives in the androstane and estrane serie s the 16-oxo-17 beta-benzyl-17 alpha-hydroxy derivatives 6 and 7 with inversed configuration at C-17 were obtained. A mechanism for this nov el rearrangement is proposed. (C) 1997 Published by Elsevier Science L td.